Microsoft Defender for Business
Microsoft's endpoint protection and EDR for smaller companies, included in Microsoft 365 Business Premium and sold on its own.
- Works with Microsoft 365
Endpoint protection is the software on each laptop, desktop and server that decides whether a file or process is allowed to run. Older antivirus compared files against a list of known malware. The products listed here add machine learning models that judge files and behavior they have never seen, which matters because most malware today is changed slightly for each victim so it won't match a list.
EDR, short for endpoint detection and response, goes a step further. The agent records what happens on the machine: which programs started, what they launched, which files they touched and where they connected. When something looks wrong, an admin can open that history, see how the attack started, isolate the machine from the network with one click and kill the process. For a ransomware attack, that record is often the only way to learn which account was stolen and which other machines were reached.
For a small business, the hard part of EDR is staffing it. An EDR tool produces alerts, and many of them need a person to decide whether they are real. If nobody reads them, the tool works like plain antivirus. That is why most vendors here sell a managed version, often called MDR, where their analysts watch your alerts and contain threats for you, and why many small companies buy endpoint security through an MSP that runs the console.
Before you choose, list every device the tool must cover. Windows laptops are supported everywhere, but Mac, Linux servers, phones and tablets vary by product and by tier. Check what the cheapest bundle includes. Many vendors keep EDR history, device isolation or threat hunting for higher tiers, and sell the entry tier as next-generation antivirus.
Ask how the product handles ransomware in particular. Some watch for mass file encryption and stop it partway, and a few can roll changed files back on Windows. Ask what happens when the device is offline, how tamper protection stops an attacker with admin rights from uninstalling the agent, and how updates are pushed.
What a featured listing costs ยท from $99 a month
Microsoft's endpoint protection and EDR for smaller companies, included in Microsoft 365 Business Premium and sold on its own.
Cloud-managed endpoint protection and EDR that runs as one lightweight agent, with bundles sized for small businesses.
Endpoint platform with on-device AI detection, automatic rollback of ransomware changes on Windows, and the Purple AI assistant.
Endpoint protection with deep learning malware detection and anti-ransomware rollback, managed from Sophos Central.
Business endpoint security with machine learning detection, risk analytics and EDR, managed from one GravityZone console.
Endpoint security platform from ESET, with cloud or on-premises management, EDR in higher tiers and an MDR option.
The business security line from Malwarebytes, bundling endpoint protection, EDR and managed detection for small IT teams.
Trend Micro's security platform joining endpoint protection, email and cloud detection, with an AI assistant for analysts.
Endpoint protection and EDR that classifies running applications in the cloud, managed alongside WatchGuard firewalls.
Unified security platform covering antivirus, patching, privilege control and DNS filtering from one agent and console.
Look at the console as well as the agent. A small IT team needs to see at a glance which devices are unprotected, out of date or offline, and to push policy to groups of machines without visiting each one. If an MSP runs the product for you, ask for read access so you can check device coverage yourself.
Check the overlap with what you already own. Windows ships with Microsoft Defender Antivirus, and Microsoft 365 Business Premium includes Defender for Business. A third-party product usually puts Defender into passive mode, and running two active antivirus engines on one machine causes slowdowns and false alarms. Decide which product is in charge of each device.
Run a short trial on a handful of machines, including the one with the oldest software in the office. Watch for slowdowns, blocked business apps and how much tuning the alerts need. Then do a quick drill: ask the vendor or your MSP to show you how they would isolate a machine and walk you through what they found.
Endpoint protection does not replace backups, multi-factor login or email filtering. Attackers who log in with a stolen password can act through normal tools that look harmless to an endpoint agent, which is why identity monitoring and a managed SOC often sit beside it.
Antivirus decides whether to block a file or process. EDR also records what happens on the device over time and gives you tools to investigate and respond, such as isolating a machine or killing a process across the fleet. Most business products here include both, with EDR in higher tiers.
EDR still records useful history, but without someone reviewing alerts you lose most of its value. Look for a managed option where the vendor's analysts watch detections, or have an MSP run it. That is the usual setup for companies without security staff.
Running two active antivirus engines on one machine usually causes slowdowns and conflicts. Most third-party products put Microsoft Defender into passive mode. Some managed services, such as those that monitor alongside Defender, are designed to sit beside an existing engine, so ask the vendor first.
Most products in this category protect Macs, but the feature set on Mac is often smaller than on Windows. Phones and tablets are covered by some products and tiers and not others. Check the supported platforms list on the official site before you buy.
It stops many ransomware attacks, especially known strains and attacks that start with a malicious file. It can miss attacks that use a stolen admin account and normal system tools. Keep tested, offline or immutable backups as well, because they are what you restore from when prevention fails.